Noninvasive Nanobiosensing Technology

Our patented nanobiosensor utilizes advanced aptamer technology to detect estradiol molecules in sweat with exceptional specificity. By capitalizing on the electrochemical signal transduction of hormone-binding events, the device delivers accurate results with minimal sample volume. This innovation signifies a monumental shift from traditional blood-based assays, offering a noninvasive, real-time alternative that matches clinical-grade accuracy.

Unparalleled Sensitivity

Engineered for subpicomolar sensitivity, our nanobiosensor detects even the most minute fluctuations in estradiol levels. This level of precision was once only attainable in clinical settings. Now, women can continuously monitor their hormone cycles without invasive procedures, gaining access to data that empowers informed health decisions.

Real-Time Data Acquisition

Our biosensor’s real-time data acquisition system combines microfluidic sweat sampling with immediate electrochemical monitoring. Covering a dynamic detection range that spans physiological estradiol levels, the device provides an immediate and comprehensive profile of hormonal changes. This real-time capability is crucial for capturing hormone fluctuations as they occur—insights often missed by static blood tests.

This technology is the culmination of six years of intensive research, involving over $5 million of research funding and the dedicated efforts of over 20 researchers, including PhDs and postdoctoral scholars.

Nature Electronics 2023, 6, 630.
Nature Biomedical Engineering 2023, 7, 1293.
Nature Machine Intelligence, 2023, 5, 1344.
Nature Electronics 2024, 10.1038/s41928-023-01116-6.
Nature Nanotechnology, 2023,10.1038/s41565-023-01513-0.
Nature Biotechnology, 2020, 38, 217.
Science Robotics, 2020, 5, eaaz7946.
Nature Biomed Engineering 2022, 26, 1225.
Nature Reviews Chemistry, 2022, 6, 899.